Role of lipoproteins in the formation of spur cell anaemia
Medical Service, San Juan Veterans Administration Hospital, San Juan, Puerto Rico
Department of Medicine, University of Puerto Rico School of Medicine, San Juan, Puerto Rico
The case of a patient with cirrhosis of the liver suffering from severe haemolysis accompanied by circulating `spur cells' is described. Studies performed in an attempt to determine the cause for the abnormal shape of the erythrocytes demonstrated that the patient's serum could induce spur formation in normal compatible cells. Several lines of evidence pointed to the possibility that the factor inducing the spurs was a protein. By column chromatography and gradient ultracentrifugation it was shown that the patient's low density lipoproteins could induce spurs to form in normal cells.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
-
KELLER, J. W., MAJERUS, P. W., FINKE, E. H.
(1971). An Unusual Type of Spiculated Erythrocyte in Metastatic Liver Disease and Hemolytic Anemia: Report of a Case. ANN INTERN MED
74: 732-737
[Abstract]
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
