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Journal of Clinical Pathology 1984;37:564-567; doi:10.1136/jcp.37.5.564
Copyright © 1984 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

Chronic lymphocytic leukaemia terminating in acute myelofibrosis.

A L Lennard, S J Proctor

Acute myelofibrosis developed in a patient with longstanding chronic lymphocytic leukaemia who had been treated with alkylating agents and total body irradiation. The case is discussed in the context of acute non-lymphoid leukaemias occurring in chronic lymphocytic leukaemia with special reference to megakaryoblastic variants.


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