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Journal of Clinical Pathology 1989;42:483-488; doi:10.1136/jcp.42.5.483
Copyright © 1989 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

Granulocytic sarcoma of the cervix: an immunohistochemical, histochemical, and ultrastructural study.

S Banik, A B Grech, B P Eyden

Department of Histopathology, Royal Infirmary, Blackburn.

Light microscopical and routine immunohistochemical studies of a cervical neoplasm in a 32 year old woman initially suggested a histiocytic lymphoma, but histochemical staining for chloroacetate esterase established the correct diagnosis. This was supported by electron microscopic findings. Eight months later the patient developed a granulocytic sarcoma in her left breast and haemotological features of acute myeloid leukaemia. Accurate initial diagnosis of granulocytic sarcoma in a non-leukaemic patient may reduce the risk of subsequent acute myeloid leukaemia if appropriate chemotherapy is begun in time.


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