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Journal of Clinical Pathology 2000;53:940-941; doi:10.1136/jcp.53.12.940
Copyright © 2000 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.
J Clin Pathol 2000; 53:940-941
© 2000 Journal of Clinical Pathology

Short report

Chronic myeloid leukaemia occurring in a patient with hairy cell leukaemia

F A Wandroo1, D Bareford1, F El-Jehani1

1 Department of Haematology, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QH, UK

Correspondence to:
Dr Wandroo, Department of Haematology, Mid Staffordshire General Hospital, Stafford ST16 3SA, UK a.w.farooq{at}tinyonline.co.uk

Occurrences of second malignancies in hairy cell leukaemia are well recognised. Most of these malignancies are either solid tumours or lymphoproliferative disorders. The association of myeloproliferative disorders with hairy cell leukaemia (HCL) is very rare. This report describes a case of a patient with HCL who after remaining in remission developed Philadelphia chromosome positive chronic myeloid leukaemia (CML), which rapidly transformed to acute lymphoblastic leukaemia with further cytogenetic abnormalities.

Key Words: hairy cell leukaemia • chronic myeloid leukaemia • acute lymphoblastic leukaemia


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