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Published Online First: 5 April 2007. doi:10.1136/jcp.2006.043505
Journal of Clinical Pathology 2007;60:1073-1075
Copyright © 2007 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

REVIEW

Transfusion in sub-Saharan Africa: does a Western model fit?

Stephen P Field1, Jean-Pierre Allain2

1 Welsh Blood Service, Pontyclun, Wales, UK
2 Department of Haematology, University of Cambridge, Cambridge, UK; jpa1000{at}cam.ac.uk

Dr Stephen Field, Consultant in Transfusion Medicine, Welsh Blood Service, Ely Valley Road, Talbot Green, Pontyclun CF72 9WB, UK; stephen.field{at}wbs.wales.nhs.uk

ABSTRACT

This review examines the current state of transfusion services in sub-Saharan Africa and presents the argument for and against the Western model of a centralised blood service with 100% voluntary non-remunerated blood donors as advocated by the World Health Organization. The current practice of family replacement donors in hospital-based blood service is the most economical option, but in the face of high child and maternal mortality rates the blood supply has proved to be insufficient. With estimates of 5–10% of HIV transmission in Africa being the result of contaminated blood transfusions, there is a need to improve testing for transfusion transmissible diseases and the selection of blood donors. Of major concern, with respect to testing, is the quality of kits being used and the continuity of supply. The need to produce components is discussed in the context of the transfusion needs in sub-Saharan Africa. The running costs of establishing and maintaining centralised blood services need careful consideration as such projects need to be sustainable in the future. It is concluded that both options are viable while centralised programmes are being developed, and a pragmatic approach should be taken to ensure that the patients’ needs are met and that resources are suitably utilised to ensure sustainability.

Keywords: blood transfusion; sub-Saharan Africa; models; economic


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