Journal of Clinical Pathology 2008;61:1140-1141
CASE REPORTS
Neurologically presenting Whipple disease: case report and review of the literature
1 Cardiff University, University Hospital of Wales, Heath Park, Cardiff
2 South Tyneside NHS Foundation Trust, South Shields, Tyne and Wear, UK
Mr M Buckle, University Hospital of Wales, Heath Park, Cardiff, UK; bucklemj{at}cardiff.ac.uk
A previously healthy male with subacute onset right leg weakness was suspected to have an astrocytoma as imaging showed a lesion. Subsequent biopsy showed the presence of foamy macrophages containing periodic acid-Schiff staining granules, suggesting Whipple disease as a possible diagnosis.
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