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Journal of Clinical Pathology 2009;62:387-401; doi:10.1136/jcp.2008.059782
Copyright © 2009 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

MY APPROACH

My approach to interstitial lung disease using clinical, radiological and histopathological patterns

K O Leslie1,2

1 Division of Anatomic Pathology, Mayo Clinic Arizona, Scottsdale, Arizona, USA
2 Mayo Clinic College of Medicine, Rochester, Minnesota, USA; leslie.kevin@mayo.edu

Correspondence to:
Professor K O Leslie, Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ 85259, USA; leslie.kevin{at}mayo.edu

ABSTRACT

The complex world of interstitial lung disease presents nearly insurmountable challenges to the general surgical pathologist faced with a lung biopsy in this setting. The pathology is often inflammatory and always requires clinical and radiological context for a relevant and clinically useful histopathological diagnosis. A pattern-based histopathological approach to interstitial lung disease provides a "map" for the general pathologist to navigate this area successfully, especially so when used with aid of the clinical and radiological patterns of presentation.


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