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Journal of Clinical Pathology 2009;62:564-566; doi:10.1136/jcp.2009.064386
Copyright © 2009 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

SHORT REPORTS

CD4 expression by mast cells in mastocytosis: a case report

E J Soilleux1, J Bowling2, K Hollowood1

1 Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
2 Department of Dermatology, Churchill Hospital, Oxford, UK

Correspondence to:
Dr E J Soilleux, Department of Cellular Pathology, John Radcliffe Hospital, Oxford OX3 9DU, UK; elizabeth.soilleux{at}orh.nhs.uk

ABSTRACT

A 59-year-old man presented with a five-year history of an asymptomatic widespread truncal rash. Cutaneous biopsies showed mastocytosis, which was shown to be CD4-positive immunohistochemically. This potential diagnostic pitfall in the discrimination of mastocytosis from a variety of other haematopoietic neoplasms, particularly mycosis fungoides, is discussed.


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