CASE REPORTS
Adiaspiromycosis mimicking widespread malignancy in a patient with pulmonary adenocarcinoma
1 Department of Histopathology, Plymouth Hospitals NHS Trust, Crownhill, Plymouth, Devon, UK
2 Department of Histopathology, Royal Devon and Exeter Foundation NHS Trust, Exeter, Devon, UK
3 Department of Thoracic and Upper GI Surgery, Royal Devon and Exeter Foundation NHS Trust, Exeter, Devon, UK
4 Exeter Oncology Center, Royal Devon and Exeter Foundation NHS Trust, Exeter, Devon, UK
5 HPA Mycology Reference Laboratory, Bristol, UK
Correspondence to:
Correspondence to Dr Jemimah L Denson, Department of Histopathology, Plymouth Hospitals NHS Trust, Derriford Road, Crownhill, Plymouth, Devon PL6 8DH, UK; jem_denson{at}yahoo.co.uk
Adiaspiromycosis, a mycotic disease of small animals, has rarely been reported in humans. The principle causative organism in Europe is Emmonsia crescens. Inhaled, dust-borne spores of E crescens fail to germinate in host tissue, instead increasing in size dramatically to become thick-walled, round adiapsores, which induce a granulomatous response. The pathological effects depend on the spore burden and host immunocompetence, and range from asymptomatic infection through to necrogranulomatous pneumonia, respiratory failure and, rarely, death. Diagnosis is principally made through histological examination. This report describes a case of a patient with low-grade, localised pulmonary adenocarcinoma with occult adiaspiromycosis that radiologically mimicked widespread malignancy. It is believed to be the first reported human case of adiaspiromycosis in the UK.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Google Scholar
PubMed
BMJ Learning
Topic Collections
-
JCP Education
-
Lung cancer (oncology)
-
Lung cancer (respiratory medicine)
-
Pneumonia (infectious disease)
-
TB and other respiratory infections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
