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J Clin Pathol. Published Online First: 26 October 2009. doi:10.1136/jcp.2007.050492
Copyright © 2009 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

research-article

Platelet contamination causing Staphylococcus aureus septicaemia

Hazel Coutinho*, Angela Galloway, Katherine Adjukiewicz, Victoria Cleeve

Royal Victoria Infirmary,Newcastle, United Kingdom

Correspondence to: Hazel Coutinho, Microbiology, City Hospitals Sunderland, Microbiology, 3,Cresswell Drive,Gosforth, Newcastle upon Tyne, S, United Kingdom; hcrasto{at}aol.com

Accepted October 2, 2009

Abstract

Platelet transfusions have the highest incidence of post transfusion sepsis compared to any other blood products.1 Recent reports suggest that platelet related bacteraemia occurs at a frequency approximately 50 times greater than that for red blood cells.2 The source is usually skin contaminants from the donor and several organisms have been implicated, the commonest of which are coagulase negative staphylococci. We present a case of serious Staphylococcus aureus sepsis following platelet transfusion and discuss relevant methods to detect and prevent bacterial contamination.


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