research-article
Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence.
1 EV Med Research, United States;
2 Torrance Memorial Medical Center, United States;
3 South Bay Gastroenterology Medical Group, United States;
4 Pennisula pulmonary Institute, United States
Correspondence to: , ; evmed{at}sbcglobal.net
Accepted September 1, 2009
A number of infections have been associated with myalgia encephalomyelitis/chronic fatigue syndrome (ME/CFS). Often occurring in epidemics, enteroviruses are significant causes of respiratory, gastrointestinal infections, non-specific flu-like illnesses, and many disseminated infections. It has been difficult to demonstrate causality for chronic diseases without having well-documented cases of acute enterovirus infections. In this report, we described 3 patients presenting with acute enterovirus infections, which were followed by ME/CFS, and the persistent viral infections were demonstrated by finding enterovirus VP1 protein and RNA in the stomach.
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