Register for email alerts and news feeds:
This journal | BMJ Group
rss
Journal of Clinical Pathology 2001;54:161-162; doi:10.1136/jcp.54.3.161
Copyright © 2001 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.
J Clin Pathol 2001; 54:161-162
© 2001 Journal of Clinical Pathology

Editorial

Application of quantitative techniques for the assessment of gastric atrophy

A M Zaitoun, C O Record

Department of Histopathology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH, UK abd.Zaitoun@mail.qmcuh-tr.trent nhs.uk
Department of Medicine, The Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK

Atrophic gastritis is seen as the result of long standing Helicobacter pylori infection and recent studies have shown that circulating IgG antibodies to CagA are associated with this condition. Gastric atrophy is also seen in patients with pernicious anaemia caused by an immunological derangement associated with parietal cell antibodies. Non-immunological causes of atrophic gastritis include chronic alcoholism, bile reflux, drugs, partial gastrectomy, chronic pancreatitis, and liver cirrhosis. The clinical importance of gastric atrophy is that it significantly increases the risk for the development of gastric carcinoma. The prevalence of gastric atrophy is very variable but it can be detected in up to 25% of patients referred for upper gastrointestinal endoscopy. In the Sydney system of classification of gastritis a four grade scale is used: no atrophy and mild, moderate, or severe atrophy. Despite this, agreement among histopathologists for the recognition and grading of gastritis remains poor. The paper by Van . . . [Full text of this article]


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

This article has been cited by other articles:

  • Rubio, C. A (2007). My approach to reporting a gastric biopsy. J. Clin. Pathol. 60: 160-166 [Abstract] [Full Text]  

This Article

Services
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

Pathology jobs

Pathology jobs

Show me all >>