CORRESPONDENCE

Androgen receptor expression in ductal carcinoma in situ of the breast: relation to oestrogen and progesterone receptors

M Kasami¹ and D L Page²

¹ Shizuoka Cancer Center Hospital, Naga-Izumi, 411–8777, Japan
² Department of Pathology, Rm-C-3309, MCN, Vanderbilt University Medical Center, 1161 21st Av. So., Nashville, TN 37232–2561, USA; david.page@mcmail.vanderbilt.edu

Keywords: ductal carcinoma in situ; breast tumours; androgen receptors; CAG repeats

The first 150 words of the full text of this article appear below.

We wish to add a reference to the list included in the paper of Selim and colleagues¹ concerning androgen receptors in ductal carcinoma in situ (DCIS) of the breast that appeared in the Journal of Clinical Pathology in the first issue of 2002. Although the authors state¹ that androgen receptors in DCIS have not been reported previously, we had studied this and published a paper² dealing with our observations, in addition to CAG repeat lengths in the androgen receptor in DCIS.

1. Selim AG, El-Ayat G, Wells CA. Androgen receptor expression in ductal carcinoma in situ of the breast: relation to oestrogen and progesterone receptors. J Clin Pathol 2002;55:14–16.[Abstract/Free Full Text]
2. Kasami M, Gobbi H, Dupont WD, et al. Androgen receptor CAG repeat lengths in ductal carcinoma in situ of breast, longest in the apocrine variety. The Breast 2000;9:23–7.

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Authors’ reply

A A Selim³, G El-Ayat³ and C A Wells³

³ Department of Histopathology, St Bartholomew's Hospital, St Bartholomew's and the Royal School of Medicine and Dentistry, Queen Mary and Westfield College, University of London, West Smithfield, London EC1A 7BE, UK;
aaselim@doctors.net.uk

Thank you for this information and the opportunity to reply. Unfortunately, the study of androgen receptor (AR) CAG repeats by Kasami and colleagues¹ is not included in the usual searches and this appears to be the reason for overlooking this reference. In this study, cases of fibroadenoma, ductal carcinoma in situ (DCIS), and invasive mammary carcinoma were included. Twenty four cases of DCIS were tested for AR CAG repeats . . . [Full text of this article]

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