© 2004 BMJ Publishing Group Ltd & Association of Clinical Pathologists
ECHO
T vaginalis screening goes global
| The first 150 words of the full text of this article appear below. |
A large study in Africa could help to control the HIV epidemic there, through routine screening for Trichomonas vaginalis, which can predispose to HIV infection. The study concluded that a latex agglutination test, by virtue of its simplicity, is a realistic prospect for screening in poor countries.
Sensitivity of the test was higher than for "wet preparation"—microscopic examination of a vaginal swab sample (98.8 v 81.5)—and equivalent to culture (98.2)—the definitive test for T vaginalis. Specificity, at 92.1, was satisfactory. Agreement between latex agglutination and the other tests was good (0.93 agglutination/culture; 0.88 agglutination/wet preparation). The test requires minimal equipment and training; results are available within two minutes.
Vaginal swab samples were taken by a nurse from all 206 women positive for T vaginalis by latex agglutination of initial samples obtained themselves and 412 selected women with negative initial samples out of 3807 consecutive women attending antenatal clinics in Ghana
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