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Journal of Clinical Pathology 2007;60:720-722; doi:10.1136/jcp.2006.044198
Copyright © 2007 by the BMJ Publishing Group Ltd & Association of Clinical Pathologists.

CASE REPORT

Metastatic renal oncocytoma

J D Oxley1, J Sullivan2, A Mitchelmore3, D A Gillatt4

1 Department of Cellular Pathology, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol, UK
2 Department of Urology, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol, UK
3 Department of Radiology, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol, UK
4 Department of Urology, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol, UK

Correspondence to:
Correspondence to:
J D Oxley
Department of Cellular Pathology, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK;jon.oxley@nbt.nhs.uk

Accepted 17 October 2006

The first 150 words of the full text of this article appear below.

Renal oncocytomas are classified as benign renal neoplasms in the 2004 World Health Organization classification of renal tumours.1 Cases of metastatic tumours have been documented,2–4 but subsequent reports have identified subtypes of renal tumours having similar histological morphology but having malignant potential. These tumours have been classified as either eosinophilic variants of renal cell carcinoma (RCC) or chromophobe carcinomas. Differentiating these tumours from oncocytomas has proved to be difficult and relies on a combination of histological morphology, immunohistochemistry and electron microscopy. There is still a presumption that if metastasis occurs then the tumour should not be classified as a renal oncocytoma and should be called an eosinophilic RCC.

We present a patient who presented with liver metastasis 9 years after the removal of a renal oncocytoma.

Case report

A woman in her 70s presented with left-sided abdominal pain. She was noted to have a mobile mass in the left upper quadrant. . . . [Full text of this article]


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Relevant Article

Renal oncocytoma, yet another tumour that does not fit in the dualistic benign/malignant paradigm?
Th. Van der Kwast, B Perez-Ordoñez
J. Clin. Pathol. 2007 60: 585-586. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

  • Aslam, M. I., Spencer, L., Garcea, G., Pollard, C., Metcalfe, M. S., Harrison, R. F., Dennison, A. R. (2009). A Case of Liver Metastasis From an Oncocytoma With a Focal Area of Chromophobe Renal Cell Carcinoma: A Wolf in Sheep's Clothing. INT J SURG PATHOL 17: 158-162 [Abstract]  
  • Kwast, Th. V. d., Perez-Ordonez, B (2007). Renal oncocytoma, yet another tumour that does not fit in the dualistic benign/malignant paradigm?. J. Clin. Pathol. 60: 585-586 [Full Text]  

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