Article Text
Short reports/Case reports
Implications of increased haemoglobin A2 values in HIV positive women in the antenatal clinic
Abstract
Universal antenatal haemoglobinopathy screening in this hospital has identified several women with increased haemoglobin A2 values, but without hypochromic microcytic red cell indices. This report describes two cases where there is evidence that the raised haemoglobin A2 value is not caused by heterozygous β thalassaemia, but rather results from these patients being human immunodeficiency virus (HIV) positive and on antiretroviral therapy. This will have important implications as universal antenatal haemoglobinopathy screening becomes more widespread, and as the number of HIV positive women of childbearing age increases.
- Hb, haemoglobin
- HIV, human immunodeficiency virus
- MCH, mean cell haemoglobin
- MCV, mean cell volume
- human immunodeficiency virus positive
- haemoglobin A2 values
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Footnotes
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The patients gave their permission for these details to be published.