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Children’s vaccines do not induce cross reactivity against SARS-CoV
  1. Yang Yu1,
  2. Huali Jin1,
  3. Ze Chen2,
  4. Qingling L Yu1,
  5. Yijie J Ma1,
  6. Xiaolin L Sun1,
  7. Bin Wang1
  1. 1State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, China
  2. 2Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China
  1. Correspondence to:
 Dr B Wang
 State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, 2 Yuanmingyuan Xi Road, Beijing 100094, China; bwang3{at}cau.edu.cn

Abstract

In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.

  • SARS, severe acute respiratory syndrome
  • SARS CoV, SARS coronavirus

https://doi.org/10.1136/jcp.2006.038893

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    Footnotes

    • This work was supported by a research initiation grant from China Agricultural University to BW.

    • Competing interests: None.