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A SIMPLE METHOD FOR THE DETERMINATION OF SERUM HAPTOGLOBINS
  1. J. A. Owen*,
  2. F. C. Better,
  3. J. Hoban
  1. Clinical Biochemical Laboratory, St. Vincent's Hospital, Melbourne, Australia

    Abstract

    Changes in the serum haptoglobin level have been reported in certain forms of anaemia (Allison and ap Rees, 1957; Allison, 1958; Nosslin and Nyman, 1958; Nyman, Gydell, and Nosslin, 1959), in hepatobiliary disease (Owen, Mackay, and Got, 1959) and in various inflammatory and chronic diseases (Jayle and Boussier, 1955; Allison and Blumberg, 1958). A simple colorimetric procedure for the determination of serum haptoglobins is presented. It is based on the peroxidase activity of haptoglobin-methaemoglobin complexes.

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    Footnotes

    • * In receipt of a grant from the National Health and Medical Research Council of Australia.