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POLYCYTHAEMIA VERA AND CHRISTMAS DISEASE WITH SLIGHTLY PROLONGED PROTHROMBIN TIME
  1. J. A. S. Amos*
  1. Royal South Hants Hospital, Southampton

    Abstract

    A family is reported in which Christmas disease in one member and polycythaemia in another were associated with prolongations of the one-stage prothrombin time of the factor-VII deficiency type.

    Changes in the prothrombin time were present in the siblings of the case of Christmas disease and in a number of unrelated cases of polycythaemia vera.

    The use of “mixing procedures” did not reveal any significant mutual correction of the changes in prothrombin time.

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    Footnotes

    • * Present address: Department of Pathology, Redhill County Hospital, Surrey.

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