Article Text

PDF

THE DIFFERENTIAL DIAGNOSIS OF TUMOUR CELLS IN CIRCULATING BLOOD
  1. R. F. Alexander,
  2. A. I. Spriggs
  1. Churchill Hospital, Headington, Oxford

    Abstract

    White-cell concentrates were made by a dextran sedimentation technique from the blood of 140 cases of malignant disease and 60 controls. The slides were searched for tumour cells and for other unusual cells with which they might be confused. Several million white cells were scanned in the slides from each case.

    Acceptable tumour cells were identified in the blood of seven patients, none of whom survived for more than a few months. These cells are illustrated, as well as various other cell types which may have been confused with malignant cells in the past. It is concluded that the cytology of white cell concentrates should be further explored before statistics about the occurrence of circulating tumour cells are accepted.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.