Article Text

PDF

FOLIC ACID AND OTHER ABSORPTION TESTS IN LYMPHOSARCOMA, CHRONIC LYMPHOCYTIC LEUKAEMIA, AND SOME RELATED CONDITIONS
  1. W. R. Pitney,
  2. R. A. Joske*,
  3. Norma L. Mackinnon
  1. Department of Haematology, Royal Perth Hospital, Perth, Western Australia
  2. Department of Medicine, University of Western Australia, Perth, Western Australia

    Abstract

    An improved folic acid absorption test is described in detail.

    Using the folic acid and other absorption tests, a study of intestinal function has been made in eight patients with lymphosarcoma, eight with chronic lymphocytic leukaemia, two with Hodgkin's disease, and one each with reticulum cell sarcoma, Whipple's disease, and macroglobulinaemia. It was found that laboratory evidence of intestinal malabsorption was extremely common in patients with this group of diseases.

    The folic acid absorption test was the most sensitive single index of malabsorption of the tests used in this study.

    Correlation between the different absorption tests was poor, and there does not appear to be a characteristic biochemical profile of intestinal function in these patients.

    Statistics from Altmetric.com

    Footnotes

    • * Adolph Basser Research Fellow in Medicine, Royal Australasian College of Physicians.

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.