The 24-hour urinary excretion of 5-hydroxyindoleacetic acid in women with post-menopausal flushing attacks was compared with that of a control group of post-menopausal women without flushing attacks. The results were normal in the women with post-menopausal flushing, and it is concluded that 5-hydroxytryptamine is not a factor in the pathogenesis of post-menopausal flushing.
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