Paper tests for occult blood were assessed on faecal specimens from adults. An orthotolidine/sodium perborate and a modified orthotolidine/peroxide test were found to be reasonably satisfactory. The Hematest and Occultest tablets and a paper guaiac test were unsatisfactory.
A large number of false positive results was obtained in children and infants. It is suggested that this might be due to meat derivatives reaching the faeces more easily in the young.
Red cells labelled with either Cr51 or Fe59 were swallowed by human volunteers. Although between 45% and 73% of the red cell iron reappeared in the faeces, the peroxidase activity of the labelled material dropped six-fold on passage through the alimentary canal.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.