Agglutination tests with various sera and leucocytes from 58 leukaemic patients and 61 patients without leukaemia are reported.
The agglutination of white blood cells by guinea-pig serum is of limited value in the diagnosis of leukaemia, though the test may be helpful in distinguishing leukaemia from other lymphomatous disorders.
Leuco-autoagglutinins were demonstrated more frequently than expected. Eleven leukaemic and six non-leukaemic sera agglutinated autologous leucocytes.
White blood cell agglutinins showed no apparent relationship to maturity or numbers of circulating leucocytes or to previous blood transfusions, x-irradiation, or therapy with antimetabolites.
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