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Estimation of serum L. casei activity
  1. I. Chanarin,
  2. Valerie Berry
  1. Medical Research Council Experimental Haematology Research Unit and Department of Haematology, Wright-Fleming Institute of Microbiology, St. Mary's Hospital Medical School, London

    Abstract

    Measurement of the serum Lactobacillus casei (`folic-acid') activity is widely used as an index of folic-acid deficiency. Present methods of assay result in recovery of about half the active material in normal serum. A modified method of assay is described which gives higher L. casei values and a clearer distinction between the sera of normal subjects and of patients with folic-acid deficiency.

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