The histological diagnosis in 77 cases of the nephrotic syndrome occurring in Uganda is presented. Plasmodium malariae was detected in 31 cases and all but one of these showed diffuse proliferative or focal glomerulonephritis. Pure membranous glomerulonephritis was seen in nine cases; none of these had parasitaemia. Children (63%) had a higher incidence of parasitaemia than adults (40%) in the cases examined.
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