Article Text

PDF

Inherited thrombocytopenia with thrombasthenia
  1. N. K. Sheth,
  2. T. A. J. Prankerd
  1. Department of Clinical Haematology, University College Hospital, London

    Abstract

    A family with congenital thrombocytopenia is described through four generations where the mode of inheritance appears to be an autosomal dominant.

    Spontaneous bruising of varying severity, menorrhagia, and profuse bleeding at operation necessitating transfusion were predominant in the history. Platelet function tests were performed on the various patients. Platelet aggregation by adenosine diphosphate (ADP) was found to be defective, though liberation of platelet factor III and platelet thromboplastic function were found to be normal when corrected for deficient numbers.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.