Article Text


Acute hepatitis due to Herpes simplex virus in an adult
  1. T. H. Flewett,
  2. R. G. F. Parker,
  3. W. M. Philip
  1. East Birmingham Hospital, Birmingham


    A case is described of herpetic hepatitis in a pregnant woman with primary herpetic stomatitis. Intranuclear inclusion bodies and virus particles were found in hepatocytes, and herpes virus was isolated from a liver biopsy and from oral swabs but not from blood. From rising titres of neutralizing and complement-fixing antibody it is concluded that the oral infection was a primary one. Factors predisposing to the hepatitis are discussed.

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