Article Text

PDF

Comparison of quick and slow thaw methods of producing cryoprecipitate antihaemophilic factor from fresh and 24-hour-old blood
  1. A. L. Bloom,
  2. J. C. Giddings,
  3. Beryl Bevan,
  4. M. Letton,
  5. R. J. Drummond
  1. Institute of Pathology, the Royal Infirmary, Cardiff
  2. Welsh Regional Transfusion Centre, Rhyd-lafar, Cardiff

    Abstract

    Cryoprecipitate antihaemophilic factor concentrate was prepared from fresh and 24-hour-old blood by quick and slow thaw methods. Recovery of factor VIII was greater by the slow thaw method and there was less loss into the supernatant plasma. Cryoprecipitate produced from fresh blood contained more factor VIII than that produced from 24-hour-old blood so that the most potent concentrate was produced from fresh blood by the slow thaw process. An adequate therapeutic preparation was, however, produced by the slow thaw method using 24-hour-old blood and it is suggested that this procedure could be adopted in order to supplement supplies.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Linked Articles