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Histochemical similarities between newborn and leukaemic myeloid cells and their possible significance
  1. Paul L. Wolf1,
  2. Boris Silberberg,
  3. Samuel Albert,
  4. Jerome Horwitz,
  5. Elisabeth Von Der Muehill
  1. Department of Pathology, Stanford University Medical Center, Wayne State University School of Medicine, Detroit General Hospital, Hutzel Hospital, USA
  2. Detroit Institute of Cancer Research, USA


    The neutrophilic alkaline phosphatase activity of 40 newborns was determined and found to be frequently raised, similarly to a leukaemoid reaction. The newborn neutrophil has strong alkaline phosphatase activity and is unlike the myeloid leukaemia cell which has no alkaline phosphatase activity.

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    • 1 Present address: Clinical Laboratory, Stanford University Medical Center, Stanford, California 94305.

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