Article Text

PDF

Congenital nephrotic syndrome and renal vein thrombosis in infancy
  1. F. Alexander1,
  2. W. A. B. Campbell
  1. Institute of Pathology, Queen's University of Belfast

    Abstract

    Three of the four cases of the nephrotic syndrome in infancy described show the typical clinical and pathological features of the commonly termed congenital nephrotic syndrome, and two of them abnormal immunoglobulins. Two of the infants were siblings. The placental abnormalities and renal electron microscopic changes are reported and are believed to be involved in antigen-antibody reactions. The literature is reviewed and the possible aetiology of these lesions is discussed. The fourth case is considered to be due to thrombosis of the inferior vena cava and renal veins, an extremely rare cause of the nephrotic syndrome in infants.

    Statistics from Altmetric.com

    Footnotes

    • 1 Present address: Department of Pathology, Foothills Hospital, Calgary, Alberta, Canada.

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.