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Ascorbic acid status in iron-deficiency anaemia
  1. A. Jacobs,
  2. D. Greenman,
  3. E. Owen,
  4. I. Cavill
  1. Department of Haematology, Welsh National School of Medicine, Cardiff

    Abstract

    Leucocyte ascorbic acid concentration declines with age. Patients with iron-deficiency anaemia have higher concentrations than normal while those with iron overload have a reduced concentration. It is suggested that these phenomena may be a result of reduced ascorbate catabolism in iron-deficiency anaemia and they provide support for the suggestion that the amount of iron in the tissues may be an important factor in determining ascorbic acid utilization.

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