Article Text

PDF

Medullary carcinoma of the thyroid with parathyroid adenoma and hypercalcaemia
  1. J. B. MacGillivray,
  2. C. J. B. Anderson
  1. Department of Pathology, Maryfield Hospital, Dundee
  2. Arbroath Infirmary

    Abstract

    A patient with hyperparathyroidism due to a parathyroid adenoma was found to have metastatic medullary carcinoma in lymph nodes close to the thyroid gland. The finding of normal calcitonin and parathormone concentrations after removal of the adenoma suggested that the parathyroid lesion was not the result of the hypocalcaemic action of calcitonin produced by the tumour in the thyroid.

    Seventeen other examples of the association between medullary carcinoma and parathyroid enlargement are briefly reviewed.

    The pathogenesis of the parathyroid lesions is discussed, and it is suggested that some may be caused by the hypocalcaemic action of calcitonin, while others may be part of a syndrome of multiple endocrine adenomatosis.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.