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A method for the quantitation of small intestinal biopsy specimens
  1. M. S. Dunnill,
  2. R. Whitehead
  1. Gibson Laboratories, Radcliffe Infirmary, Oxford

    Abstract

    A simple method is described for the quantitative examination of small intestinal mucosal biopsies involving the determination of an index related to the surface-to-volume ratio of the mucosa. The method is of value in distinguishing minor degrees of villous abnormality and will prove useful in comparing serial changes in a given patient. It will also allow comparisons to be made between biopsies taken in different medical centres.

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