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Australia antigen and antibody in British patients with leprosy
  1. Tin Shwe,
  2. A. J. Zuckerman
  1. Department of Clinical Tropical Medicine and Burma Leprosy Service
  2. Department of Bacteriology and Immunology, London School of Hygiene and Tropical Medicine

    Abstract

    Seventy-five sera collected from leprosy patients in England were tested for Australia antigen and antibody. Australia antigen was detected in only two patients with lepromatous leprosy and in one patient with borderline pure leprosy. Antibody to Australia antigen was found in one patient with lepromatous leprosy. These findings differ from previous reports and it is suggested that the frequency of Australia antigen in lepromatous leprosy is a function of the incidence of this antigen in the general population rather than increased genetic susceptibility to chronic infection.

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