Article Text

PDF

Antibody to hepatitis B antigen in haemophiliacs and their household contacts
  1. C. J. Burrell,
  2. A. C. Parker,
  3. D. M. Ramsay,
  4. Elaine Proudfoot
  1. Department of Bacteriology, Edinburgh University Medical School, Edinburgh
  2. Department of Haematology, Royal Infirmary, Edinburgh

    Abstract

    The prevalence of antibody to hepatitis B antigen, detectable by radioimmunoassay, was found to be no higher among 58 long-term household contacts of multiply transfused haemophiliacs than among 100 randomly chosen blood donors. This suggested that such contacts do not have greater exposure to serum hepatitis virus than that occurring through natural means. Among those persons possessing antibody, the multiply transfused haemophiliacs showed a marked tendency for higher antibody titres than their contacts, implying differences in pathogenesis between infection acquired through multiple transfusion and infection acquired naturally.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.