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Thymidine-dependent Escherichia coli infection and some associated laboratory problems
  1. Elizabeth I. Tanner,
  2. C. H. Bullin
  1. Public Health Laboratory, West Park Hospital, Epsom, Surrey

    Abstract

    The rapid emergence of a thymidine-dependent strain of Escherichia coli in a patient treated with co-trimoxazole is described. The organism was recovered from blood cultures during a septicaemia which developed after only a few days of co-trimoxazole treatment. The cultural characteristics of three thymidine-dependent strains were studied and a remarkable variation was found in their ability to grow on different batches of blood agar, depending upon the age of the plates and the type of agar base used.

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