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Complement fixing antibody responses to virus infection in children with acute lymphoblastic leukaemia.
  1. A W Craft,
  2. M M Reid,
  3. J McQuillin,
  4. P S Gardner

    Abstract

    Thirty children with acute lymphoblastic leukaemia (ALL) were studied and had a virus isolated. Only 50% produced a significant rise in complement fixing (CF) antibody titre compared to 100% of normal children. The failure to produce antibodies was unpredictable. CF antibodies are not a reliable guide to virus infections in children with ALL.

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