Article Text

PDF

Intracellular immunoglobulin distribution of bone marrow plasma cells as a diagnostic aid for primary amyloidosis.
  1. C Thielemans,
  2. W Aelbrecht,
  3. D Verbeelen,
  4. G Somers,
  5. M De Waele,
  6. B Van Camp

    Abstract

    In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal proliferation of light chain containing plasma cells, and thus led to the diagnosis of immunoglobulin-related amyloidosis.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.