J Clin Pathol 36:1071-1075 doi:10.1136/jcp.36.9.1071
  • Research Article

Intramucosal carcinoma of the gastric antrum complicating Menetrier's disease.


A 48-year-old man presented with haematemesis and was found to have Menetrier's disease. Three and a half years later early gastric cancer was detected at routine follow-up endoscopy. This is the first report of the development of early gastric cancer during follow-up in a case of Menetrier's disease. It is probable that patients with Menetrier's disease are at increased risk of gastric cancer, and should have regular endoscopic follow-up with gastric biopsy.