Article Text

PDF

The platelet defect in acute myeloid leukaemia.
  1. B E Woodcock,
  2. P C Cooper,
  3. P R Brown,
  4. C Pickering,
  5. D A Winfield,
  6. F E Preston

    Abstract

    In a study of platelets from 13 patients with acute myeloid leukaemia abnormal aggregation and release reactions were found. A previously unrecognised quantitative defect of thromboxane B2 production may, at least in part, explain these findings. In contrast to a previous report, we were unable to show a convincing storage pool defect in these platelets. The platelet membrane glycoproteins were largely normal.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.