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Major histocompatibility complex class II antigen expression in B and T cell non-Hodgkin's lymphoma.
  1. M E Smith,
  2. C S Holgate,
  3. J M Williamson,
  4. I Grigor,
  5. P Quirke,
  6. C C Bird

    Abstract

    An immunohistochemical study of 46 B and T cell non-Hodgkin's lymphomas, using monoclonal antibodies to the products of the major histocompatibility complex (MHC) class II antigen subregions, DP, DQ, and DR, showed that most B and T cell lymphomas express these antigens. Both coordinate and non-coordinate expression of MHC class II antigens was observed, but this did not correlate with immunological phenotype, morphological grade, or proliferation index as determined by flow cytometry.

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