Article Text

PDF

Chromosome 22 abnormalities in Ewing's sarcoma.
  1. E V Davison,
  2. A D Pearson,
  3. J Emslie,
  4. M M Reid,
  5. A Malcolm,
  6. A W Craft
  1. Department of Human Genetics, University of Newcastle upon Tyne.

    Abstract

    A child with disseminated Ewing's sarcoma underwent cytogenetic investigations which showed different structural rearrangements of chromosome 22 at diagnosis (?ring22), and at relapse [t(10;22)], but the classic translocation t(11;22) was not detectable. This case provides further evidence of the importance of chromosome 22 in this disease, while raising some questions about the central importance of the translocation between chromosomes 11 and 22.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.