Article Text

PDF

Xanthoderma: an unusual presentation of hypothyroidism.
  1. M A al-Jubouri,
  2. E J Coombes,
  3. R M Young,
  4. N P McLaughlin
  1. Department of Chemical Pathology, Queen Alexandra Hospital, Cosham, Portsmouth.

    Abstract

    A young woman presented with progressive yellowing of her skin over a period of six months. Liver function tests were requested by her general practitioner and the results prompted the Chemical Pathology Department to instigate further tests to reach the final diagnosis. Hypercarotenaemia had caused her yellow skin, and various other biochemical abnormalities pointed towards primary hypothyroidism as an underlying cause. Thyroxine replacement treatment successfully corrected all the biochemical abnormalities including hypercarotenaemia. As far as is known, yellow skin as a sole presenting feature of hypothyroidism is extremely rare.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.