Article Text

PDF

CD10 positive thyroid marginal zone non-Hodgkin lymphoma.
  1. E K Millar,
  2. S Waldron,
  3. A Spencer,
  4. S Braye
  1. Department of Anatomical Pathology, John Hunter Hospital, Hunter Region Mail Centre, Lambton, Australia. emillar@doh.health.nsw.gov.au

    Abstract

    A 72 year old woman presented with swelling of the right lobe of her thyroid gland. Fine needle aspiration and flow cytometry showed a clonal population of B cells expressing CD10 and a diagnosis of follicle centre cell lymphoma was made. Subsequent excision of the thyroid showed the typical histological features of a marginal zone non-Hodgkin lymphoma. Polymerase chain reaction showed no evidence of t (14;18). Immunohistochemistry confirmed CD10 positivity and LN1 (CDw75) expression. This is only the second report of aberrant expression of CD 10 by a marginal zone lymphoma.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.