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Thrombophilia testing
  1. P T Murphy1
  1. 1Department of Haematology, Royal Shrewsbury Hospital, Shrewsbury SY3 8XG, UK

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    In his recent leader, Dr Baglin gives an interesting overview of thrombophilia testing. However, his clinical practice of screening all unselected patients with an episode of venous thromboembolism is at odds with the British committee for standards in haematology guidelines on the investigation of thrombophilia.2 According to these guidelines, the main indications for thrombophilia testing are patients with a venous thromboembolism before the age of 45 years, recurrent venous thrombosis or thrombophlebitis, thrombosis in an unusual site, or a first venous thromboembolism with a clear family history of venous thrombosis. Such restrictions on expensive and time consuming thrombophilia tests to patient groups more likely to have underlying thrombophiliac defects are almost mandatory for haematology departments working under the financial constraints of the present day national health service.


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