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Letters to JCP
The culture of lactobacilli species in gastric carcinoma
  1. P J Roberts1,
  2. R J Dickinson1,
  3. A Whitehead2,
  4. C R Laughton3,
  5. J E Foweraker3
  1. 1Department of Gastroenterology, Hinchingbrooke Hospital, Hinchingbrooke Park, Huntingdon, Cambridgeshire PE29 6NT, UK
  2. 2Department of Histopathology, Hinchingbrooke Hospital
  3. 3Department of Microbiology, Papworth Hospital, Cambridgeshire, UK

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      Filamentous organisms have been reported in brushings and biopsies from both benign and malignant gastric ulcers,1,2 but these have not been characterised and their importance is unknown. In a preliminary study of tissue samples obtained at laparotomy from malignant gastric ulcers we cultured Lactobacillus spp, which are recognised commensals in the upper gastrointestinal tract,3 but not normally present in the stomach.

      In view of the previous culture of Lactobacilli spp in surgically excised gastric tumours, we prospectively sought evidence of Lactobacilli spp infection of benign and malignant gastric ulcers …

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