Article Text

Download PDFPDF
Symptomatic laryngeal nodular chondrometaplasia: a clinicopathological study
  1. A Orlandi1,
  2. S Fratoni1,
  3. I Hermann2,
  4. L G Spagnoli1
  1. 1Institute of Anatomic Pathology, Tor Vergata University, Rome, Italy
  2. 2Otorhinolaringoiatry, European Hospital, Rome, Italy
  1. Correspondence to:
 Professor A Orlandi
 Institute of Anatomic Pathology, Department of Biopathology, Tor Vergata University, Via Montpellier 1, Rome, Italy; orlandiuniroma2.it

Abstract

A 41 year old man with a history of politrauma presented with a nodular mass of the left false vocal cord, associated with progressive dysphonia, dyspnoea, and dysphagia. A computed tomography scan of the neck region showed a rounded and circumscribed mass without infiltration of the surrounding tissues. Histological investigation of the nodule revealed the presence of fibroelastic cartilaginous tissue, surrounded by a thin rim of fibrous tissue, with rare hypercellular areas, occasional binucleated cells, slight hyperchromasia, and an irregular nuclear profile. Mitotic activity was absent. The patient’s history of laryngeal trauma, with the subsequent progressive onset of clinical symptoms, helps to distinguish the chondrometaplastic nature of this nodule from true laryngeal cartilaginous tumours, such as chondroma and low grade chondrosarcoma.

  • Cartilaginous tumour
  • chondrometaplasia
  • larynx

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes