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TGF-β and transglutaminase 2 work together to cause cataracts

https://doi.org/10.1136/jcp.56.2.141

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    A molecular study has shown for the first time that transglutaminase 2 (TGase 2) overexpression induced by transforming growth factor β (TGF-β) is a key step in the development of some cataracts.

    The investigators showed TGase 2 mRNA and TGase 2 protein in human lens epithelial cells taken from anterior …

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