You are here

  • Home
  • Archive
  • Volume 57, Issue 10
  • Adenocarcinoma arising in villous adenoma of the ampulla of Vater with synchronous malignant gastrointestinal stromal tumour of the duodenum: a case report

Article Text

Article menu
Download PDFPDF
Correspondence
Adenocarcinoma arising in villous adenoma of the ampulla of Vater with synchronous malignant gastrointestinal stromal tumour of the duodenum: a case report
  1. N H Aksoy1,
  2. C Çevikol2,
  3. M Ögüş3,
  4. G Ö Elpek4,
  5. T Gelen4
  1. 1Department of Pathology, Akdeniz University, School of Medicine, 07070 Antalya, Turkey; nazifhikmet@akdeniz.edu.tr
  2. 2Department of Radiology, Akdeniz University, School of Medicine
  3. 3Department of Surgery, Akdeniz University, School of Medicine
  4. 4Department of Pathology, Akdeniz University

    https://doi.org/10.1136/jcp.2004.018143

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

      An association between ampullary adenoma and adenocarcinoma has been reported previously.1 However, we believe that this is the first report of the synchronous occurrence of adenocarcinoma of the ampulla of Vater and a gastrointestinal stromal tumour (GIST).

      A 41 year old woman was admitted to our hospital for the evaluation of jaundice. Her liver function tests were as follows: alanine aminotransferase, 37 U/litre (normal range, 0–31); aspartate aminotransferase, 32 U/litre (normal range, 0–32); alkaline phosphatase, 598 U/litre (normal range, 0–240); total bilirubin, 203.2 mg/litre (normal range, 1–11); direct biluribin, 151.6 mg/litre (normal range, 0–3).

      Ultrasonography, computed tomography, and magnetic resonance imaging studies showed intrahepatic and extrahepatic bile duct dilatation. Termination of the common bile duct at the distal end by a mass was noted (fig 1). The initial radiological differential diagnosis included pancreatic …

      View Full Text